Cubs Rally from 4-Run Deficit, Top Reds 5-4 in 10
Soriano singled in the seventh and scored Chicago's first run off Johnny Cueto on Luis Valbuena's two-out single.
Anthony Rizzo hit an RBI double against Logan Ondrusek in the eighth - his third double in two games - and Soriano followed with his fifth homer of the season and first since May 13, a 394-foot drive to left-center.
J.J. Hoover (0-4) walked Scott Hairston with two outs in the 10th, and Castillo followed with his double into the left-field corner.
Kevin Gregg (1-0) pitched 1 1-3 hitless innings, stopping the Reds' five-game winning streak.
See other LocalSports news:Andy Dalton's 3 TD Passes Lead Bengals Over Rams 31-7
Southern Illinois beats Portland 80-79
Upshall Leads Blues Past Blue Jackets 3-1
Gaborik's 2 Goals Rally Kings to 3-2 OT Win Over Blackhawks
No. 17 Northwestern Beats Illinois 24-14 for 10th Win